Why undergoing this examination?

Variation in the human genome is one of the factors responsible for modulating individual responses to medications. Pharmacogenetics studies how genetic differences between individuals influence their responses to drugs. The metabolism of a drug consists of several reactions that modify it and, in general, convert it into a more soluble molecule that can be more easily excreted. Various genes responsible for the expression of enzymes involved in drug metabolism pathways have genetic variants that cause changes in enzyme expression, selectivity, or activity, which result in diverse drug responses. Consequently, the assessment of genetic profiles based on the analysis of these variants has become essential to aid in understanding drug metabolism.

What is the exam?

The MyPharma Neuro pharmacogenetic panel evaluates variants in genes responsible for the expression of the main enzymes involved in the metabolism of medications most commonly used in the treatment of neurological and psychiatric conditions, such as depression, anxiety, schizophrenia, bipolar disorder, among others. The analysis provides relevant information on 62 active ingredients currently most widely used in medicine, based on the study of genetic variants described in the scientific literature and present in 121 genes.

For whom is it indicated?

• Patients with neurological or psychiatric conditions, such as depressive, psychotic, anxiolytic, or hypnotic disorders, who wish to personalize treatment based on their genetic profile;
• Patients on polypharmacy;
• Patients for whom pharmacological treatments have not produced the expected results and whose symptoms persist despite medication;
• Patients experiencing significant side effects from medications.

Technology

SNAP Array