Por que realizar este exame?

The liquid biopsy allows performing before and during the treatment an analysis of the changes related to the resistance of the drug that is administered to the patient. In this sense, it was observed that the detection of some of these alterations can predict the progression of the disease, thus giving the professional an opportunity to modify and adjust the treatment earlier without the need for invasive procedures, such as biopsy of the tumor tissue.

O que é o exame?

Analysis of blood changes (fluid biopsy) with diagnostic, predictive and prognostic relevance that allow the detection and monitoring of mutations directed and related to mechanisms of drug resistance.                                                                                                Each profile of ONCOinBLOOD is indicated for the diagnosis, follow-up and monitoring of different pathologies:
ONCOinBLOOD – ALK:
• Patients with non-small cell lung cancer and others.
ONCOinBLOOD – BRAF:
• Patients with colorectal cancer, metastatic melanoma, thyroid tumors, non-small cell lung cancer and others.
ONCOinBLOOD – EGFR:
• Patients with non-small cell lung cancer.
ONCOinBLOOD – EML4-ALK:
• Patients with non-small cell lung cancer.
ONCOinBLOOD – KRAS:
• Patients with non-small cell lung cancer, colorectal cancer, pancreatic cancer, and other.
ONCOinBLOOD – MET:
Patients with non-small cell lung cancer.
ONCOinBLOOD – PIK3CA:
• Patients with non-small cell lung cancer and breast cancer.

Para quem é indicado?

Indicated for cancer patients in the following cases:
• Insufficient amount of biopsied tissue, unsuitable sample quality for NGS or when biopsy must be obtained from difficult access tissue;
• Biopsy tissue of ≥ 6 months;
• Critical treatment and decision is needed in 2 weeks or less;
• Patient prefers a non-invasive evaluation.

Tecnologia

5’ Nuclease PCR assay

Vantagens

SYNLAB GROUP:
• Guaranteed from the experience of the Synlab group, the absolute European leader in laboratory diagnosis.                                                                                                            MINIMALLY INVASIVE:
• Allows the genetic analysis of the tumor from a patient’s blood sample in a short time.
RELIABLE:    
• High sensitivity (75-78%) and specificity (100%, no false positives were detected) being able to detect 1 free DNA molecule between 20,000.

Informações Extras

DOCUMENTATION – Available on Extranet for clients:
• Informed Consent.
• Clinical Questionnaire.
PREPARATION:
• Fasting is not necessary for the test.


Tempo de Entrega
11 working days
Tipo de Amostra
2 mL of serum and 2 mL of plasma

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