Why undergoing this examination?

Thrombophilia is the propensity for thrombi development and occurs as a consequence of changes in the coagulation system. Thrombophilia is potentiated in pregnancy and puerperium due to the procoagulant characteristics of these conditions.  They can be classified as: acquired and hereditary thrombophilia and affect approximately 15% of the overall population.

The risk of venous thromboembolism (VTE) during pregnancy and the puerperium is increased between 9 and 34 times in women with genetic thrombophilia. Gestational complications caused by thrombophilia can be described as placental thrombosis, severe forms of gestational hypertension, premature placental detachment, intrauterine fetal growth restriction, which may progress to fetal death. These complications represent about 75% of the causes of neonatal morbidity and mortality.

What is this exam?

The analysis consists of the evaluation of 12 genetic variants associated with an increased risk of developing thrombosis: The result is obtained through a mathematical algorithm that makes it possible to assess the patient’s risk in three ways: the patient’s risk of having thrombophilia associated with the current clinical condition (variable factors such as weight, smoking, habits and lifestyle); patient risk compared to the risk of heterozygosity for Factor V Leiden, with the same clinical profile, and the risk with the same clinical profile considering the genetic variants found. Enabling a complete analysis of the genetic implications for the risk of thrombophilia and, in turn, of recurrent pregnancy loss.

For whom is it indicated?
  • Women who:
    – Experience recurrent fetal losses or miscarriages
    – Are pregnant and have venous thrombosis
  • – Are being treated with oral contraceptives- Patients with a family history of venous thromboembolism
Technology

Reverse Transcription Polymerase Chain Reaction (RT-PCR)

Advantages

SYNLAB GROUP:

  • Guaranteed from the experience of the SYNLAB group, the absolute European leader in laboratory diagnosis.

COMPLETE:

  • Objective and detailed results report.
Extra information

DOCUMENTATION – Available on Extranet for clients:

  • Informed Consent.
  • Clinical Questionnaire.PREPARATION:
  • Fasting is not necessary to undergo the examination.

Delivery Time
20 working days
Type of Sample
5 mL of whole blood EDTA tube

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